MIT engineers are likely to design a future wound dressing that is based on a sticky, ductile, gel-like material that can be embedded in temperature sensors, LED lights, and other electronic devices. At the same time, it is also possible to establish a tiny drug delivery channel and a drug storage reservoir. This "smart wound dressing" can change the release of the drug according to the temperature of the skin surface, and it can light up when the drug is insufficient. When used in areas with more frequent movements such as knees or elbows, the dressing can extend with the body while the embedded electronic device operates as usual.
The key to the design of this smart dressing is thanks to the designer of the hydrogel matrix, Xuanhe Zhao, an assistant professor of mechanical engineering at MIT. He also designed a matrix LED lamp embedded in a layer of hydrogel. Even if it is attached to different parts of the body, such as elbows and knees, the gel can still function normally.
Zhao also has great expectations for the hydrogel matrix, thinking that this material is an ideal biological device that can be used to transfer electronic devices into living organisms. He is currently investigating the possibility of using a hydrogel matrix as a glucose sensor and nerve detection device. Traditional glucose sensing devices have to be implanted in the body and usually cause foreign body reaction to the system, so that the immune system starts an alarm. This causes the outer layer of the sensor to be covered with layers, so that the doctor must often replace the new sensor and implant it in the body. .
Different hydrogel matrices have been used to coat glucose sensors and successfully block reactions that are coated by layers of the immune system. The hydrogel matrix is ​​relatively fragile and easily decomposes on the fly. But the hydrogel sensing system developed by their team is likely to have high toughness and long life.
At present, researchers are trying to use different soft materials, hoping to successfully develop a neural device with biological compatibility. Through collaboration, we are trying to apply the hydrogel matrix to neural devices because hydrogels can be designed to have mechanical and physiological properties very similar to that of the brain.
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